| Event | Time | Date | Name | Meet | History |
|---|---|---|---|---|---|
| 50 Free | 22.17 | Jan. 1, 2002 | Mularz, Mandy | - | |
| 100 Free | 48.72 | Jan. 22, 2024 | Arielle Hayon | Rice vs Miami | |
| 200 Free | 1:45.69 | Dec. 6, 2013 | Casey Clark | - | |
| 500 Free | 4:42.13 | March 20, 2008 | Brittany Massengale | NCAA Division I Womens Championships | |
| 1000 Free | 9:47.86 | Jan. 1, 2008 | Brittany Massengale | - | |
| 1650 Free | 15:57.73 | Jan. 1, 2008 | Brittany Massengale | - | |
| 50 Back | 24.73 | Feb. 15, 2023 | Zoe Spitz | American Athletic Conference Championships | |
| 100 Back | 52.80 | Feb. 17, 2023 | Zoe Spitz | American Athletic Conference Championships | |
| 200 Back | 1:54.01 | Feb. 25, 2023 | Zoe Spitz | Texas A&M Last Chance Meet | |
| 50 Breast | 28.48 | March 14, 2024 | Siiri Einio | CSCAA National Invitational Championship | |
| 100 Breast | 59.68 | March 1, 2019 | Marie-Claire Schillinger | Conference USA Championships | |
| 200 Breast | 2:09.67 | March 2, 2019 | Marie-Claire Schillinger | Conference USA Championships | |
| 50 Fly | 23.97 | March 10, 2022 | Arielle Hayon | CSCAA National Invitational Championship | |
| 100 Fly | 51.38 | Feb. 24, 2024 | Arielle Hayon | American Athletic Conference Championships | |
| 200 Fly | 1:56.26 | Feb. 18, 2023 | Arielle Hayon | American Athletic Conference Championships | |
| 100 IM | 54.98 | March 16, 2024 | Imogen MEERS | CSCAA National Invitational Championship | |
| 200 IM | 1:58.55 | Feb. 23, 2024 | Arielle Hayon | American Athletic Conference Championships | |
| 400 IM | 4:11.43 | March 9, 2018 | Kaitlyn Swinney | CSCAA National Invitational Championship | |
| 200 Free Relay | 1:30.02 | Feb. 24, 2022 | Howe, McDougall, Cano Minarro, Evans | Conference USA Championships | |
| 400 Free Relay | 3:18.95 | Feb. 26, 2022 | Howe, McDougall, Evans, Cano Minarro | Conference USA Championships | |
| 800 Free Relay | 7:07.77 | Feb. 27, 2019 | Cano Minarro, Therien, Parish, Mathys | Conference USA Championships | |
| 200 Medley Relay | 1:37.04 | Feb. 19, 2015 | Caldwell, Moody, Clark, Konicke | Conference USA Championships | |
| 400 Medley Relay | 3:28.42 | Jan. 22, 2024 | Ussishkin, Einio, Hayon, MEERS | Rice vs Miami |
