| Time | Date | Name | Meet |
|---|---|---|---|
| 3:18.95 | Feb. 26, 2022 | Howe, McDougall, Evans, Cano Minarro | Conference USA Championships |
| 3:19.30 | March 2, 2019 | Nezelek, Gillentine, Mathys, Cano Minarro | Conference USA Championships |
| 3:19.32 | March 1, 2014 | McKenzie, Clark, Konicke, Wlostowska | Conference USA Championships |
| 3:19.80 | Nov. 23, 2013 | Fong, Konicke, Clark, Wlostowska | Phill Hansel Invitational |
| 3:21.03 | Feb. 23, 2013 | Clark, Fong, Konicke, Wlostowska | Conference USA Championships |
| 3:21.16 | Dec. 17, 2012 | Clark, Fong, Konicke, Wlostowska | Incarnate Word Christmas Invitational |
| 3:21.66 | Feb. 28, 2009 | Conference USA Championships - Day Four - Finals | |
| 3:30.67 | Nov. 6, 2008 | Rice @New Mexico State | |
| 3:34.74 | March 6, 2003 | Keith, Healey, Taheri, Lee | American Short Course Championships |
