| Event | Time | Date | Name | Meet | History |
|---|---|---|---|---|---|
| 50 Free | 22.15 | March 19, 2015 | Isabella Arcila-Hurtado | NCAA Division I Womens Championships | |
| 100 Free | 47.87 | March 21, 2015 | Martina Moravcova | - | |
| 200 Free | 1:43.08 | Feb. 17, 2012 | Martina Morvacova | - | |
| 500 Free | 4:37.72 | March 13, 2003 | Flavia Rigamonti | - | |
| 1000 Free | 9:31.64 | March 15, 2003 | Flavia Rigamonti | - | |
| 1650 Free | 15:40.41 | March 15, 2003 | Flavia Rigamonti | - | |
| 50 Back | 24.23 | Feb. 20, 2013 | Isabella Arcila-Hurtado | - | |
| 100 Back | 51.99 | March 15, 2012 | Therese Svendsen | NCAA Division I Womens Championships | |
| 200 Back | 1:52.17 | March 15, 2008 | Anja Carman | - | |
| 50 Breast | 29.43 | Dec. 16, 2018 | Erin Trahan | OK KMSC King Marlin Pro-AM | |
| 100 Breast | 58.93 | Dec. 4, 2015 | Rachel Nicol | - | |
| 200 Breast | 2:08.66 | March 2, 2019 | Andrea PODMANIKOVA | American Athletic Conference Championships | |
| 50 Fly | 23.90 | Dec. 15, 2018 | Erin Trahan | OK KMSC King Marlin Pro-AM | |
| 100 Fly | 51.10 | March 21, 2014 | Marne Erasmus | NCAA Division I Womens Championships | |
| 200 Fly | 1:56.44 | March 2, 2019 | Erin Trahan | American Athletic Conference Championships | |
| 100 IM | 1:00.28 | Feb. 4, 2023 | Caroline Sullivan | SMU Pre Conference Invite | |
| 200 IM | 1:58.04 | Feb. 17, 2022 | Gabi Grobler | American Athletic Conference Championships | |
| 400 IM | 4:05.52 | Feb. 17, 2017 | Matea Samardzic | American Conference Championships | |
| 200 Free Relay | 1:22.61 | Nov. 1, 2008 | - | ||
| 400 Free Relay | 3:03.25 | Jan. 6, 2009 | - | ||
| 800 Free Relay | 6:30.00 | Feb. 25, 2009 | - | ||
| 200 Medley Relay | 1:32.04 | Nov. 1, 2008 | Penn State @Southern Methodist | ||
| 400 Medley Relay | 3:17.31 | Jan. 30, 2009 | - |
