| Event | Time | Date | Name | Meet | History |
|---|---|---|---|---|---|
| 50 Free | 22.58 | Feb. 23, 2017 | Sierra Wagner | Mid-American Championships (W) | |
| 100 Free | 48.72 | March 22, 2008 | Maddy Pilchard | NCAA Division I Womens Championships | |
| 200 Free | 1:45.36 | March 21, 2008 | Maddy Pilchard | NCAA Division I Womens Championships | |
| 500 Free | 4:43.84 | Feb. 28, 2019 | Nicole Swartz | Mid-American Championships (W) | |
| 1000 Free | 9:57.35 | Jan. 19, 2019 | Nicole Swartz | Eastern Michigan vs. Buffalo | |
| 1650 Free | 16:03.51 | Dec. 2, 2011 | Briana Emig | Eastern Michigan Invitational | |
| 50 Back | 24.66 | Feb. 22, 2017 | Alexis Mitcheltree | Mid-American Championships (W) | |
| 100 Back | 52.57 | Feb. 24, 2017 | Alexis Mitcheltree | Mid-American Championships (W) | |
| 200 Back | 1:55.33 | March 2, 2019 | Casey Gavigan | Mid-American Championships (W) | |
| 50 Breast | 29.25 | March 14, 2024 | Nina LaRosa | CSCAA National Invitational Championship | |
| 100 Breast | 57.83 | March 22, 2019 | Delaney Duncan | NCAA Division I Womens Championships | |
| 200 Breast | 2:07.38 | March 2, 2019 | Delaney Duncan | Mid-American Championships (W) | |
| 50 Fly | 25.78 | Feb. 29, 2024 | Katarina Pastar | Mid-American Championships (W) | |
| 100 Fly | 54.19 | Feb. 26, 2016 | Carly Jackson | Mid-American Championships (W) | |
| 200 Fly | 1:58.35 | Nov. 30, 2012 | Jessie GODLEWSKI | Eastern Michigan Invitational | |
| 100 IM | 59.39 | Oct. 19, 2019 | Claire Young | Buffalo vs. Bowling Green, Cornell | |
| 200 IM | 1:59.45 | Feb. 28, 2019 | Delaney Duncan | Mid-American Championships (W) | |
| 400 IM | 4:14.08 | Feb. 23, 2018 | Nicole Swartz | Mid-American Championships (W) | |
| 200 Free Relay | 1:31.60 | Feb. 25, 2016 | Wagner, Detro, Mitcheltree, Maclean | Mid-American Championships (W) | |
| 400 Free Relay | 3:21.42 | Feb. 22, 2009 | Mid-American Conference Championships - Day Four - Finals | ||
| 800 Free Relay | 7:15.92 | Feb. 25, 2015 | GODLEWSKI, Detro, Dorszewski, Van Allen | Mid-American Championships (W) | |
| 200 Medley Relay | 1:37.95 | Feb. 22, 2017 | Mitcheltree, Duncan, Liberman, Wagner | Mid-American Championships (W) | |
| 400 Medley Relay | 3:36.33 | Feb. 24, 2017 | Mitcheltree, Duncan, Jackson, Van Allen | Mid-American Championships (W) |
