| Time | Date | Name | Meet |
|---|---|---|---|
| 4:09.55 | March 23, 2017 | Fynn Minuth | NCAA Division I Mens Championships |
| 4:11.07 | Feb. 15, 2017 | Fynn Minuth | Southeastern Conference Championships |
| 4:12.59 | March 24, 2016 | Ahmed Mahmoud | NCAA Division I Mens Championships |
| 4:12.78 | Feb. 17, 2016 | Ahmed Mahmoud | Southeastern Conference Championships |
| 4:15.11 | Feb. 18, 2015 | Ahmed Mahmoud | Southeastern Conference Championships |
| 4:15.32 | Feb. 20, 2013 | Michael Flach | Southeastern Conference Championships |
| 4:16.03 | Feb. 17, 2011 | Michael Flach | Southeastern Conference Championships |
| 4:19.37 | Feb. 18, 2010 | Michael Flach | Southeastern Conference Championships |
| 4:22.37 | March 15, 2007 | Dan White | NCAA Division I Mens Championships |
