| Time | Date | Name | Meet |
|---|---|---|---|
| 2:49.27 | Feb. 22, 2020 | Casas, Theall, Bratanov, Koster | SEC Championship |
| 2:49.99 | Nov. 23, 2019 | Casas, Koster, Bratanov, Theall | Art Adamson Invitational |
| 2:52.01 | March 25, 2017 | Bolleter, Koster, Gonzales, Ayar | NCAA Division I Mens Championships |
| 2:52.49 | March 26, 2011 | Dalton, Troskot, Lindau, Makany | NCAA Division I Mens Championships |
| 2:52.76 | Feb. 26, 2011 | Makany, Dalton, Lindau, Troskot | Big 12 Conference Championships |
| 2:52.89 | March 28, 2010 | Makany, Strange, Dalton, Loncaric | NCAA Division I Mens Championships |
| 2:53.72 | March 28, 2009 | Makany, Raiford, Clarke | NCAA Division I Mens Championships |
| 2:54.58 | Feb. 28, 2009 | Big 12 Conference - Day Four - Finals | |
| 2:55.25 | March 29, 2008 | Strange, Chambless, Raiford, Gardner | NCAA Division I Mens Championships |
| 3:05.39 | March 6, 2003 | Moeller, Kemp, Benson, Waguespack | American Short Course Championships |
| 3:06.34 | Feb. 20, 2003 | Watson, Benson, Kemp, Waguespack | Speedo Champions Series - College Station |
