| Time | Date | Name | Meet |
|---|---|---|---|
| 50.09 | Feb. 18, 2023 | Clara Williams | Patriot League Championships |
| 50.17 | April 17, 2021 | Madison Berg | Army vs. Navy |
| 50.33 | Feb. 22, 2020 | Madison Berg | Patriot League Championships |
| 50.36 | Feb. 20, 2016 | Monica Sowinski | Patriot League Championships |
| 50.42 | Dec. 10, 2015 | Kelly Hamilton | Navy vs. Army |
| 50.74 | Feb. 18, 2012 | Paige Brink | Patriot League Championships |
| 51.91 | Dec. 4, 2011 | Grace Hamilton | Zippy Invitational |
| 52.34 | Feb. 19, 2011 | Paige Brink | Patriot League Championships |
| 52.43 | Feb. 20, 2010 | Paige Brink | Patriot League Championships |
| 52.63 | Feb. 21, 2009 | Cortney Heaps | Patriot League Championships - Day Three - Finals |
