| Time | Date | Name | Meet |
|---|---|---|---|
| 2:53.25 | Feb. 24, 2024 | Dragoja, Sivaramakrishnan, Matic, Rodgers | Atlantic 10 Championships |
| 2:55.68 | April 17, 2021 | Mlynarczyk, OSINA, Pone, Kawakami | Atlantic 10 Championships |
| 2:56.63 | Feb. 23, 2019 | Fath, Auster, Forstenhausler, Lersch | Atlantic 10 Conference Championships |
| 2:56.89 | March 10, 2018 | Forstenhausler, Lersch, Fath, Auster | CSCAA National Invitational Championship |
| 2:57.11 | Feb. 17, 2018 | Hokfelt, Forstenhausler, Auster, Drury | Atlantic 10 Conference Championships |
| 2:58.72 | Feb. 18, 2017 | Drury, Forstenhausler, Bolognesi, Hokfelt | Atlantic 10 Conference Championships |
| 3:00.60 | Feb. 20, 2016 | Drury, Bolognesi, Lersch, Hokfelt | Atlantic 10 Conference Championships |
| 3:01.09 | Feb. 21, 2015 | Drury, Hokfelt, Balteanu, Koprivnjak | Atlantic 10 Conference Championships |
| 3:02.13 | Feb. 26, 2011 | Graeter, Seedorff, Etz, Wilson | Atlantic 10 Conference Championships |
| 3:04.38 | Feb. 21, 2009 | Atlantic 10 Championships - Day Four - Finals |
