| Time | Date | Name | Meet |
|---|---|---|---|
| 52.64 | March 1, 2019 | JA ARENTEWICZ | American Athletic Conference Championships |
| 53.00 | Feb. 20, 2015 | Rokas Cepulis | American Conference Championships |
| 53.88 | Feb. 28, 2014 | Rokas Cepulis | Conference USA Championships |
| 54.23 | Feb. 17, 2012 | Rokas Cepulis | Conference USA Championships |
| 54.72 | Feb. 26, 2010 | Travis Stauder | Conference USA Championships |
| 55.64 | Feb. 27, 2009 | Travis Stauder | Conference USA Championships - Day Three - Finals |
| 58.11 | Nov. 20, 2008 | Tommy Ryan | Gamecock Invite |
| 58.68 | Oct. 11, 2008 | Tommy Ryan | Xavier, East Carolina, West Virginia @Marshall |
