| Name | Time | Date | Meet |
|---|---|---|---|
| Nicole Swartz | 4:14.08 | Feb. 23, 2018 | Mid-American Championships (W) |
| Briana Emig | 4:15.87 | Dec. 3, 2011 | Eastern Michigan Invitational |
| Briana Emig | 4:15.93 | Feb. 25, 2011 | Mid-American Conference Womens Championships |
| Sam Partridge | 4:20.06 | Feb. 21, 2009 | 2009 Mid-American Conference Championships - Day Three - Finals |
| Leeza Moser | 4:34.71 | Nov. 15, 2008 | 2008 Purdue Challenge |
