| Time | Date | Name | Meet |
|---|---|---|---|
| 21.86 | April 9, 2021 | Riley Lohse | Horizon League Championships |
| 22.24 | Feb. 19, 2020 | Riley Lohse | Horizon League Championships |
| 22.62 | Jan. 24, 2020 | Riley Lohse | Oakland vs. IUPUI |
| 22.66 | Feb. 17, 2016 | Aaron Brysch | Summit League Championships |
| 22.90 | Jan. 22, 2016 | Aaron Brysch | IUPUI vs. Wabash |
| 23.01 | Nov. 21, 2015 | Aaron Brysch | IUPUI House of Champions Invitational |
| 23.05 | Feb. 18, 2015 | Tony Carroll | Summit League Championships |
| 23.27 | Feb. 19, 2014 | Tony Carroll | Summit League Championships |
| 23.86 | Nov. 23, 2013 | Tony Carroll | House of Champions Invitational |
| 24.03 | Nov. 9, 2013 | Tony Carroll | IUPUI vs. Wright St |
| 24.05 | Feb. 15, 2012 | Tony Carroll | Summit League Championships |
| 25.03 | Oct. 15, 2011 | Tony Carroll | Indiana Intercollegiates |
| 25.23 | Feb. 19, 2010 | Michael Steurer | Summit League Championships |
| 25.72 | Nov. 14, 2009 | Michael Steurer | House of Champions Invite |
| 26.13 | Oct. 10, 2009 | Tyler McGowan | Indiana Intercollegiates |
