| Time | Date | Name | Meet |
|---|---|---|---|
| 44.81 | Feb. 19, 2023 | Shaun Kronenwetter | NESCAC Mens Championships |
| 45.40 | Feb. 22, 2015 | Vincent Galea | NESCAC Men's Championships |
| 46.17 | Feb. 24, 2013 | Vincent Galea | New England Small College Athletic Conference Mens Championships |
| 46.33 | Feb. 28, 2010 | Ben Gross | New England Small College Athletic Conference (M) Championships |
| 49.88 | Dec. 5, 2009 | Ben Gross | MIT Invitational |
