| Time | Date | Name | Meet |
|---|---|---|---|
| 50.17 | Feb. 15, 2024 | Myles Felt | North Coast Athletic Conference Championships |
| 51.64 | Feb. 10, 2023 | Myles Felt | North Coast Athletic Conference Championships |
| 51.83 | Feb. 22, 2014 | Marshall Waller | Kenyon College Invitational |
| 52.88 | Feb. 13, 2014 | Marshall Waller | North Coast Athletic Conference Championships |
| 53.02 | Feb. 11, 2011 | Dylan Jordan | North Coast Athletic Conference Championships |
| 53.52 | Feb. 10, 2011 | Dylan Jordan | North Coast Athletic Conference Championships |
| 54.25 | Dec. 3, 2009 | Nick Lashway | Wooster Invitational |
| 54.65 | Nov. 22, 2008 | Nick Lashway | Oberlin @ Baldwin-Wallace |
