| Time | Date | Name | Meet |
|---|---|---|---|
| 49.23 | Feb. 15, 2024 | Michael Kohl | Southern Collegiate Athletic Conference Championships |
| 49.41 | Nov. 18, 2022 | Michael Kohl | Tiger Invitational |
| 49.77 | Feb. 16, 2018 | Robert Clark | Southern Collegiate Athletic Conference Championships |
| 49.81 | Nov. 18, 2017 | Robert Clark | Trinity Invitational |
| 49.83 | Feb. 10, 2017 | Charles Clark | Southern Collegiate Athletic Conference Championships |
| 50.28 | Feb. 12, 2016 | Isaac Johnson | Southern Collegiate Athletic Conference Championships |
| 50.88 | Feb. 13, 2015 | Isaac Johnson | Southern Collegiate Athletic Conference Championships |
| 52.11 | Feb. 17, 2012 | Stephen Culberson | Southern Collegiate Athletic Conference Championships |
| 52.71 | Feb. 16, 2012 | Stephen Culberson | Southern Collegiate Athletic Conference Championships |
| 52.90 | Feb. 18, 2011 | Sean Fronczak | Southern Collegiate Athletic Conference Championships |
| 52.96 | Feb. 17, 2011 | Andrew Battles | Southern Collegiate Athletic Conference Championships |
| 53.36 | Feb. 18, 2010 | Sean Fronczak | Southern Collegiate Athletic Conference Championships |
| 55.60 | Nov. 21, 2009 | Sean Fronczak | Trinity Western Shootout |
