| Event | Time | Date | Name | Meet | History |
|---|---|---|---|---|---|
| 50 Free | 23.92 | Feb. 21, 2020 | Shawyuan Hsu | New England Womens and Mens Athletics Conference Championships | |
| 100 Free | 52.32 | Feb. 20, 2022 | Jessica Wegner | New England Womens and Mens Athletics Conference Championships | |
| 200 Free | 1:53.63 | Feb. 22, 2020 | Hannah May | New England Womens and Mens Athletics Conference Championships | |
| 500 Free | 5:03.79 | Feb. 21, 2014 | Keelin Nave | New England Womens and Mens Athletics Conference Championships | |
| 1000 Free | 10:39.30 | Nov. 22, 2013 | Leah Furman | Wellesley vs. MIT | |
| 1650 Free | 17:22.78 | Feb. 23, 2014 | Leah Furman | New England Womens and Mens Athletics Conference Championships | |
| 50 Back | 26.10 | Feb. 16, 2013 | Dorothy Ren | New England Womens and Mens Athletics Conference Championships | |
| 100 Back | 56.65 | Feb. 18, 2023 | Tracey Liu | New England Womens and Mens Athletics Conference Championships | |
| 200 Back | 2:04.08 | Jan. 24, 2016 | Dorothy Ren | Seven Sisters Championships | |
| 50 Breast | 30.24 | Jan. 20, 2024 | Kavita Sekhon | Sisters Invitational | |
| 100 Breast | 1:02.37 | Feb. 24, 2024 | Kavita Sekhon | NEWMAC Championships | |
| 200 Breast | 2:18.02 | Feb. 25, 2024 | Kavita Sekhon | NEWMAC Championships | |
| 50 Fly | 25.99 | Feb. 24, 2019 | Jessica Wegner | New England Womens and Mens Athletics Conference Championships | |
| 100 Fly | 55.30 | Feb. 19, 2022 | Jessica Wegner | New England Womens and Mens Athletics Conference Championships | |
| 200 Fly | 2:03.38 | March 23, 2012 | Keelin Nave | NCAA Division III Championships | |
| 100 IM | 58.96 | Feb. 20, 2022 | Jessica Wegner | New England Womens and Mens Athletics Conference Championships | |
| 200 IM | 2:08.14 | Feb. 17, 2023 | Aubrey Cantrell | New England Womens and Mens Athletics Conference Championships | |
| 400 IM | 4:34.55 | Feb. 19, 2022 | Cecilia Cai | New England Womens and Mens Athletics Conference Championships | |
| 200 Free Relay | 1:37.32 | Feb. 23, 2024 | Mitsuoka, Tang, Liu, Sekhon | NEWMAC Championships | |
| 400 Free Relay | 3:31.87 | Feb. 23, 2020 | Hsu, Peterson, Wegner, May | New England Womens and Mens Athletics Conference Championships | |
| 800 Free Relay | 7:41.68 | Feb. 18, 2016 | Harris, Wang, Ren, Galinyte | New England Womens and Mens Athletics Conference Championships | |
| 200 Medley Relay | 1:43.93 | Feb. 18, 2023 | Liu, Sekhon, Cantrell, Mitsuoka | New England Womens and Mens Athletics Conference Championships | |
| 400 Medley Relay | 3:50.52 | Feb. 17, 2023 | Liu, Sekhon, Cai, Mitsuoka | New England Womens and Mens Athletics Conference Championships |
