| Time | Date | Name | Meet |
|---|---|---|---|
| 2:51.35 | March 2, 2024 | Tiffany, Camacho Salgado, Reed, Riva | Big XII Conference Championships |
| 2:52.25 | Feb. 18, 2023 | Harrison, Camacho Salgado, Riva, Nicolas | Mountain Pacific Sports Federation Championships |
| 2:53.11 | Feb. 20, 2016 | Taylor, Jenkins, Stirling, Sorenson | Mountain Pacific Sports Federation Championships |
| 2:53.88 | Dec. 5, 2015 | Stirling, Jenkins, Taylor, Sorenson | Texas Hall of Fame Swimming Invitational |
| 2:55.02 | Feb. 23, 2013 | Sorenson, Jenkins, Beaman, Murray | Mountain Pacific Sports Federation Championships |
| 2:56.36 | March 15, 2007 | Allen, Patience, Azevedo, Price | NCAA Division I Mens Championships |
