| Time | Date | Name | Meet |
|---|---|---|---|
| 43.12 | March 16, 2024 | Ian Cooper | NCAA Division II Championship |
| 43.51 | Nov. 17, 2023 | Caleb Brandon | Gamecock Invitational |
| 43.59 | March 11, 2023 | Santiago Aguilera | NCAA Division II Championship |
| 43.71 | March 12, 2016 | Jeremy Parker | NCAA Division II Championships |
| 43.89 | Dec. 20, 2015 | Jeremy Parker | Tampa Spartan Invitational |
| 44.06 | Jan. 1, 2006 | Cole Tedhams | - |
