| Time | Date | Name | Meet |
|---|---|---|---|
| 1:25.77 | Feb. 22, 2024 | Jauregui, Stumpf, Johnson, Ehrenfeld | Liberty League Championships |
| 1:25.81 | Feb. 17, 2022 | Glazebnik, Li, Pham, Ehrenfeld | Liberty League Championships |
| 1:26.26 | Feb. 20, 2014 | Amodio, Walker, Quinn, Cristina | UNYSCSA/Empire 8 Championships |
| 1:26.31 | Feb. 21, 2013 | Duhaney, Cristina, Hale, Amodio | UNYSCSA/Empire 8 Championships |
| 1:27.42 | Feb. 26, 2010 | Smart, Duhaney, Molina, Shiman | Upper New York State Collegiate Swimming Association Championships |
| 1:30.34 | Dec. 4, 2009 | Duhaney, Molina, Smart, Shiman | Liberty League Championships |
| 1:34.48 | Nov. 21, 2009 | Molina, Tully, Bernard, Hall | Vassar vs. SUNY-New Paltz |
