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| Time | Date | Name | Team | Meet |
|---|---|---|---|---|
| 4:25.44 | July 12, 2019 | Tyler Christianson | Panamanian Swimming Federation | MD NBAC Mid-Summer Classic |
| 4:25.93 | Aug. 9, 2019 | Tyler Christianson | Panamanian Swimming Federation | XVIII Juegos Panamericanos |
| 4:27.51 | Jan. 10, 2019 | Tyler Christianson | Panamanian Swimming Federation | TYR Pro Swim Series - Knoxville |
| 4:32.39 | July 31, 2011 | DIEGO CASTILLO | Panamanian Swimming Federation | 14th FINA World Championships |
| 4:39.37 | July 12, 2008 | DIEGO CASTILLO | Panamanian Swimming Federation | FINA Youth World Championships |