| Event | Time | Date | Name | Meet | History |
|---|---|---|---|---|---|
| 50 Free | 19.03 | Feb. 23, 2017 | Shane Ryan | Big Ten Conference Championships (M) | |
| 100 Free | 41.86 | Feb. 25, 2017 | Shane Ryan | Big Ten Conference Championships (M) | |
| 200 Free | 1:34.39 | March 2, 2021 | Michael Daly | B1G Men's Conference Championships | |
| 500 Free | 4:17.65 | Feb. 27, 2014 | Nick Ankosko | Big Ten Conference Championships (M) | |
| 1000 Free | 8:56.63 | Jan. 21, 2023 | Eduardo Cisternas | Penn State vs. Virginia Tech | |
| 1650 Free | 15:02.66 | March 30, 2019 | Michael Daly | NCAA Division I Mens Championships | |
| 50 Back | 20.81 | Feb. 28, 2024 | Cooper Morley | Big Ten Conference Championships (M) | |
| 100 Back | 44.65 | Feb. 24, 2017 | Shane Ryan | Big Ten Conference Championships (M) | |
| 200 Back | 1:40.22 | March 29, 2008 | Pat Schirk | NCAA Division I Mens Championships | |
| 50 Breast | 25.73 | Feb. 6, 2021 | Ben Doyle | Penn State vs. Michigan State | |
| 100 Breast | 51.08 | March 1, 2024 | Mariano Lazzerini | Big Ten Conference Championships (M) | |
| 200 Breast | 1:52.94 | March 2, 2024 | Mariano Lazzerini | Big Ten Conference Championships (M) | |
| 50 Fly | 22.34 | Feb. 6, 2021 | Tommy Hurley | Penn State vs. Michigan State | |
| 100 Fly | 44.75 | March 24, 2023 | Victor Baganha | NCAA Division I Mens Championships | |
| 200 Fly | 1:44.34 | Feb. 29, 2020 | Zac Zwijacz | Big Ten Conference Championships (M) | |
| 100 IM | 51.16 | Feb. 6, 2021 | LACHLAN BYRNE | Penn State vs. Michigan State | |
| 200 IM | 1:44.62 | Feb. 24, 2011 | Scott Marino | Big Ten Conference Mens Championships | |
| 400 IM | 3:41.09 | March 4, 2021 | Michael Daly | B1G Men's Conference Championships | |
| 200 Free Relay | 1:16.88 | March 25, 2021 | Castano, Roberson, Houck, Sutton | NCAA Division I Men's Championships | |
| 400 Free Relay | 2:51.32 | March 1, 2014 | Ryan, Hauser, Savoy, Austin | Big Ten Conference Championships (M) | |
| 800 Free Relay | 6:23.00 | Feb. 26, 2014 | Hauser, Stasiunas, BANTLEY, Heil | Big Ten Conference Championships (M) | |
| 200 Medley Relay | 1:22.93 | Feb. 28, 2024 | Morley, Lazzerini, Bittner, Baganha | Big Ten Conference Championships (M) | |
| 400 Medley Relay | 3:05.06 | Feb. 29, 2024 | Morley, Lazzerini, Bittner, Baganha | Big Ten Conference Championships (M) |
