| Name | Time | Date | Meet |
|---|---|---|---|
| Caeleb Dressel | 47.39 | June 16, 2021 | USA Olympic Team Trials - Wave 2 |
| Caeleb Dressel | 47.86 | May 19, 2019 | GA SCAT Atlanta Classic Swim Meet |
| Caeleb Dressel | 48.71 | March 7, 2019 | TYR Pro Swim Series - Des Moines |
| Brett Fraser | 49.12 | Aug. 5, 2011 | 2011 ConocoPhillips National Championships |
| Brett Fraser | 50.76 | July 20, 2008 | 2008 Speedo Champions Series - Ft. Lauderdale |
| Carlos Jayme | 51.06 | Feb. 10, 2004 | ConocoPhillips Spring National Championships |
| Carlos Jayme | 52.61 | June 28, 2002 | 2002 ATAC Long Course Open |
