| Time | Date | Name | Meet |
|---|---|---|---|
| 2:51.53 | Feb. 25, 2023 | Millard, Hodgson, Meulemans, Page | Ivy League Championships (M) |
| 2:52.25 | Feb. 29, 2020 | Page, Marcoux, Lee, Gaissert | Ivy League Championships (M) |
| 2:52.69 | Feb. 24, 2018 | Gaissert, Lin, Hyogo, Greenberg | Ivy League Championships (M) |
| 2:53.91 | Feb. 25, 2017 | Gaissert, Lin, Hyogo, Greenberg | Ivy League Championships (M) |
| 2:55.28 | March 7, 2009 | Eastern Intercollegiate Swim League Championships - Day Three - Finals | |
| 2:59.38 | March 8, 2008 | Righi, Pool, Robinson, Gurdeniz | EISL Championship |
| 2:59.74 | March 4, 2004 | Cooney, Bowman, Foss, Veazey | Men's EISL Championships |
| 3:00.30 | Feb. 28, 2002 | Cooney, Cocks, Veazey, Bowman | Men's EISL Championships |
