| Time | Date | Name | Meet |
|---|---|---|---|
| 4:18.76 | Feb. 18, 2016 | Michael Dugan | American Conference Championships |
| 4:24.47 | Feb. 27, 2014 | Michael Dugan | Conference USA Championships |
| 4:25.55 | Feb. 26, 2009 | Oliver Cavalcanti | Conference USA Championships - Day Two - Finals |
| 4:29.62 | Nov. 20, 2008 | Oliver Cavalcanti | Gamecock Invite |
| 4:37.84 | Oct. 11, 2008 | Oliver Cavalcanti | Xavier, East Carolina, West Virginia @Marshall |
