| Name | Time | Date | Meet |
|---|---|---|---|
| Logan Burton | 47.30 | March 3, 2017 | 2017 Mid-American Championships (M) |
| Krzysztof Gilski | 47.71 | March 4, 2016 | 2016 Mid-American Championships (M) |
| Krzysztof Gilski | 48.05 | March 7, 2014 | 2014 Mid-American Championships (M) |
| Justin Griggs | 48.41 | March 4, 2011 | Mid-American Conference Mens Championships |
| Ryan Fulkerson | 48.47 | Nov. 15, 2008 | 2008 Purdue Challenge |
