| Time | Date | Name | Meet |
|---|---|---|---|
| 45.24 | Nov. 15, 2023 | Jordan Tiffany | Mizzou Invitational |
| 45.34 | March 27, 2015 | Jake Taylor | NCAA Division I Mens Championships |
| 45.53 | Feb. 20, 2015 | Jake Taylor | Mountain Pacific Sports Federation Championships |
| 45.95 | Dec. 5, 2014 | Jake Taylor | Texas Invitational |
| 46.67 | Feb. 21, 2014 | Jake Taylor | Mountain Pacific Sports Federation Championships |
| 47.14 | Feb. 25, 2011 | Jake Taylor | Mountain West Conference Championships |
| 48.58 | Feb. 24, 2011 | Jake Taylor | Mountain West Conference Championships |
| 49.17 | Jan. 22, 2011 | Jake Taylor | Brigham Young vs. Wyoming |
| 49.58 | Nov. 6, 2010 | Jake Taylor | UNLV vs. Brigham Young |
| 49.82 | Feb. 28, 2009 | Jacoby Jacobsen | Mountain West Conference Championships - Day Four - Finals |
| 51.79 | Oct. 30, 2008 | Jacoby Jacobsen | Brigham Young @Texas Christian |
