| Name | Time | Date | Meet |
|---|---|---|---|
| Aaron Huynh | 45.07 | Feb. 23, 2020 | New England Womens and Mens Athletics Conference Championships |
| Charles Wang | 45.89 | Dec. 8, 2019 | WPI Gompei Invitational |
| Joe Kent | 46.50 | Feb. 19, 2012 | New England Womens and Mens Athletics Conference Womens Championships |
| Gregory Bissett | 48.23 | Feb. 27, 2011 | New England Womens and Mens Athletics Conference Mens Championships |
| Gregory Bissett | 48.55 | Oct. 24, 2009 | Clark vs. Babson |
| Mauricio Krantzberg | 50.52 | Oct. 25, 2008 | Babson vs. Clark |
