| Time | Date | Name | Meet |
|---|---|---|---|
| 2:55.05 | Feb. 18, 2023 | Jyawook, Burke, Kelly, Wickens | Horizon League Championships |
| 2:58.55 | Feb. 20, 2016 | Kuester, Wolfe, Brysch, Allen | Summit League Championships |
| 2:59.69 | Feb. 21, 2015 | Carroll, Kuester, Brysch, Allen | Summit League Championships |
| 3:00.82 | Nov. 23, 2014 | Carroll, Kuester, Wolfe, Brysch | House of Champions Invitational |
| 3:00.87 | Feb. 22, 2014 | Carroll, Kuester, Ferguson, Allen | Summit League Championships |
| 3:04.69 | Nov. 24, 2013 | Carroll, Kuester, Sunkel, Allen | House of Champions Invitational |
| 3:06.93 | Feb. 23, 2013 | Carroll, Ferguson, Howard, Sunkel | Summit League Championships |
| 3:09.51 | Feb. 18, 2012 | Carroll, Green, Hamilton, Howard | Summit League Championships |
| 3:12.16 | Feb. 22, 2009 | Summit League Championships - Day Three - Finals | |
| 3:19.92 | Oct. 17, 2008 | Butler, Centre @ IUPUI |
