| Time | Date | Name | Meet |
|---|---|---|---|
| 49.04 | March 15, 2024 | Quinn Smith | CSCAA National Invitational Championship |
| 49.36 | Feb. 10, 2023 | Sean Doran | Metro Atlantic Athletic Conference Championships |
| 49.70 | Feb. 26, 2022 | Ahmed Sallam | ECAC Open Championships |
| 49.73 | Feb. 11, 2022 | Ahmed Sallam | Metro Atlantic Athletic Conference Championships |
| 49.79 | Feb. 25, 2016 | Bobby McDowell | - |
| 49.84 | Feb. 13, 2015 | Dylan Cummings | Metro Atlantic Athletic Conference Championships |
| 50.27 | March 1, 2014 | Dylan Cummings | Eastern College Athletic Conference Championships |
| 50.40 | Feb. 13, 2014 | Dylan Cummings | Metro Atlantic Athletic Conference Championships |
| 50.81 | Feb. 18, 2011 | Nick Spinella | Metro Atlantic Athletic Conference Championships |
| 51.05 | Feb. 17, 2011 | Nick Spinella | Metro Atlantic Athletic Conference Championships |
| 52.47 | Dec. 3, 2010 | Nick Spinella | H2Ounds (Loyola) Invitational |
| 53.03 | Feb. 13, 2009 | Joshua Sklanka | Metro Atlantic Athletic Conference Championships - Day Two - Finals |
| 55.18 | Dec. 5, 2008 | Joshua Sklanka | H2ounds Invitational |
