| Time | Date | Name | Meet |
|---|---|---|---|
| 51.06 | March 24, 2023 | Reid Mikuta | NCAA Division I Mens Championships |
| 51.14 | Nov. 18, 2022 | Reid Mikuta | Georgia Fall Invitational |
| 51.32 | March 25, 2022 | Reid Mikuta | NCAA Division I Mens Championship |
| 51.33 | Nov. 19, 2021 | Reid Mikuta | Georgia Tech Invitational |
| 51.50 | Feb. 17, 2017 | Michael Duderstadt | Southeastern Conference Championships |
| 51.80 | March 27, 2009 | Adam Klein | NCAA Division I Mens Championships |
| 52.73 | Feb. 20, 2009 | Adam Klein | Southeastern Conference Championships - Day Three - Finals |
| 52.94 | March 15, 2007 | David Maras | NCAA Division I Mens Championships |
