| Time | Date | Name | Meet |
|---|---|---|---|
| 4:10.82 | March 28, 2024 | Mason Mathias | NCAA Division I Mens Championships |
| 4:11.03 | Nov. 16, 2023 | Mason Mathias | Georgia Fall Invitational |
| 4:12.15 | March 23, 2023 | Mason Mathias | NCAA Division I Mens Championships |
| 4:12.80 | March 6, 2021 | Mikkel Gadgaard | James E Martin Invitational |
| 4:14.44 | March 28, 2013 | Zane Grothe | NCAA Division I Mens Championships |
| 4:15.42 | March 22, 2012 | Zane Grothe | NCAA Division I Mens Championships |
| 4:16.57 | March 24, 2011 | Zane Grothe | NCAA Division I Mens Championships |
| 4:16.94 | Feb. 19, 2009 | Will Dove | Southeastern Conference Championships - Day Two - Finals |
| 4:20.50 | March 27, 2008 | Will Dove | NCAA Division I Mens Championships |
| 4:20.52 | March 15, 2007 | Daniel Slocki | NCAA Division I Mens Championships |
