| Time | Date | Name | Meet |
|---|---|---|---|
| 50.50 | March 25, 2022 | Liam Bell | NCAA Division I Mens Championship |
| 50.85 | March 6, 2020 | Reece Whitley | Pacific 12 Championships (M) |
| 50.86 | March 27, 2009 | Damir Dugonjic | NCAA Division I Mens Championships |
| 51.41 | Oct. 17, 2008 | Damir Dugonjic | Pacific Invitational |
| 52.50 | March 28, 2008 | Damir Dugonjic | NCAA Division I Mens Championships |
| 53.31 | March 2, 2005 | Caleb Rowe | Men's Pac-10 Championsihps |
