| Name | Team | Time | FINA | |||
|---|---|---|---|---|---|---|
| 1 | Sarah Langlois |
 Barrington Swim Club
|
2:34.93 | 539 | ||
| 2 | Addison Key |
Vipers of Albuquerque Swim Team
|
2:37.71 | 511 | ||
| 3 | Alice Han |
Barrington Swim Club
|
2:39.26 | 497 | ||
| 4 | Taylor Valade |
 Team Vortex
|
2:40.34 | 487 | ||
| 5 | Kayla Effinger |
 Dayton Raiders
|
2:42.55 | 467 | ||
| 6 | Isabel Waite |
Watertown Area Swim Club
|
2:46.49 | 435 | ||
| 7 | Katherine Reymann |
Dayton Raiders
|
2:48.56 | 419 | PB | |