| Name | Team | Time | FINA | Imp | ||
|---|---|---|---|---|---|---|
| 1 |
Alex Mathews
YMCA of the Triangle Area Swim Team
|
 YMCA of the Triangle Area Swim Team
|
644 | +4.4% | PB | |
| 2 |
Olivia Ontjes
YMCA of the Triangle Area Swim Team
|
YMCA of the Triangle Area Swim Team
|
637 | – | PB | |
| 3 |
Jenny Nusbaum
YMCA of the Triangle Area Swim Team
|
YMCA of the Triangle Area Swim Team
|
621 | – | PB | |
| 4 |
Hannah Snyder
YMCA of the Triangle Area Swim Team
|
YMCA of the Triangle Area Swim Team
|
525 | +6.2% | PB | |
| 5 |
Emily Etgen
YMCA of the Triangle Area Swim Team
|
YMCA of the Triangle Area Swim Team
|
494 | +0.4% | PB | |